N-[2-(tert-Butoxycarbonylamino)ethyl]glycine Ethyl Ester
N-(N-.beta.-Boc-aminoethyl)-Gly-OEt
CAS: 72648-80-7
Molecular Formula: C11H22N2O4
N-[2-(tert-Butoxycarbonylamino)ethyl]glycine Ethyl Ester - Names and Identifiers
N-[2-(tert-Butoxycarbonylamino)ethyl]glycine Ethyl Ester - Physico-chemical Properties
| Molecular Formula | C11H22N2O4 |
| Molar Mass | 246.3 |
| Density | 1.049±0.06 g/cm3(Predicted) |
| Melting Point | 116-119°C |
| Boling Point | 352.0±27.0 °C(Predicted) |
| Appearance | clear liquid |
| Color | Colorless to Yellow |
| pKa | 12.50±0.46(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 1.4520-1.4560 |
N-[2-(tert-Butoxycarbonylamino)ethyl]glycine Ethyl Ester - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10-21 |
N-[2-(tert-Butoxycarbonylamino)ethyl]glycine Ethyl Ester - Introduction
N-(N-.beta.-Boc-aminoethyl)-Gly-OEt (N-(N-. Boc-aminoethyl.-Gly-OEt)) is a compound with the following properties and uses:
Nature:
-Appearance: Colorless or white solid
-Molecular formula: C14H27N3O4
-Solubility: Soluble in organic solvents such as chloroform, dimethylformamide and ethanol, low solubility in water
-Storage conditions: Store in a dry, cool place, avoid light and humidity
Use:
- N-(N-.beta.-Boc-aminoethyl)-Gly-OEt are mainly used as intermediates in organic synthesis. It is commonly used in the synthesis of amino acids with protecting groups, as well as in the synthesis of peptides and proteins.
Preparation Method:
N-(N-.beta.-Boc-aminoethyl)-Gly-OEt were prepared as follows:
1. Condensation of glycine with tert-butyl hydroxymethyl carbonate and reaction under alkaline conditions to generate N-tert-butyl hydroxymethyl glycine.
2. Reaction of N-tert-butylhydroxymethylglycine with ethanol to produce N-[2-(tert-butoxycarbonylamino) ethyl] glycine ethyl ester.
3. Finally, the resulting product is reacted with hydrochloric acid to form N-(N-.beta.-Boc-aminoethyl)-Gly-OEt.
Safety Information:
- N-(N-.beta.-Boc-aminoethyl)-Gly-OEt need to operate under laboratory conditions, pay attention to personal protective measures, such as wearing gloves, glasses and lab clothes.
-Avoid direct contact with skin and eyes. If contact occurs, rinse immediately with plenty of water.
-Avoid contact with water or humid air during operation or storage.
-Pay attention to the accumulation of fire source and static electricity during the preparation process to ensure the safety of the operating environment.
-Detailed safety information should refer to the safety data sheet (MSDS) provided by the chemical supplier.
Nature:
-Appearance: Colorless or white solid
-Molecular formula: C14H27N3O4
-Solubility: Soluble in organic solvents such as chloroform, dimethylformamide and ethanol, low solubility in water
-Storage conditions: Store in a dry, cool place, avoid light and humidity
Use:
- N-(N-.beta.-Boc-aminoethyl)-Gly-OEt are mainly used as intermediates in organic synthesis. It is commonly used in the synthesis of amino acids with protecting groups, as well as in the synthesis of peptides and proteins.
Preparation Method:
N-(N-.beta.-Boc-aminoethyl)-Gly-OEt were prepared as follows:
1. Condensation of glycine with tert-butyl hydroxymethyl carbonate and reaction under alkaline conditions to generate N-tert-butyl hydroxymethyl glycine.
2. Reaction of N-tert-butylhydroxymethylglycine with ethanol to produce N-[2-(tert-butoxycarbonylamino) ethyl] glycine ethyl ester.
3. Finally, the resulting product is reacted with hydrochloric acid to form N-(N-.beta.-Boc-aminoethyl)-Gly-OEt.
Safety Information:
- N-(N-.beta.-Boc-aminoethyl)-Gly-OEt need to operate under laboratory conditions, pay attention to personal protective measures, such as wearing gloves, glasses and lab clothes.
-Avoid direct contact with skin and eyes. If contact occurs, rinse immediately with plenty of water.
-Avoid contact with water or humid air during operation or storage.
-Pay attention to the accumulation of fire source and static electricity during the preparation process to ensure the safety of the operating environment.
-Detailed safety information should refer to the safety data sheet (MSDS) provided by the chemical supplier.
Last Update：2024-04-10 22:29:15
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Product Name: N-(N-Beta-Boc-Aminoethyl)-Gly-Oet Visit Supplier Webpage Request for quotation
CAS: 72648-80-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 72648-80-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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